Boron Neutron Capture Theraphy

BNCT
BNCT
  • HOME
    • >
  • BNCT
01Selectively Destroys Tumor Cells with Neutron and Boron

It is a particle radiotherapy with a boron drug that destroys tumor cells with only one or two treatments without surgery, using boron drug which is selectively absorbed into tumor cells and neutrons generated from medical accelerators.

02Destroying tumor cells with high linear energy by particles released during fission reaction of boron

When a boron drug is injected into a cancer patient, the tumor cells selectively ingest and absorb the boron. When neutrons generated by a medical accelerator are irradiated to tumor cells, nuclear fission occurs only in such cells that have absorbed boron while passing neutrons harmless to the human body, and only tumor cells are killed without loss of normal cells by high-energy secondary particles.

  • 1. Boron administered

    Boron drug is injected into the body and selectively accumulated in tumor cells

  • 2. Neutron irradiation

    Neutrons are irradiated to the lesion using an accelerator.

  • Reaction between neutron and boron

    The high-energy alpha and lithium particles produced by nuclear capture and fission reaction by boron localized in tumor cells, kill cancer cells.

  • 3. Destroying tumor cells

    Alpha and lithium particles localized in tumor cells by drug effect does not affect normal tissues.

03Invisible cancer cells treatment is available

In principle, BNCT can treat even cells since they absorb boron drugs. Therefore, it is possible to treat invasive cancer, micro-infiltrative cancer, and dispersed cancer.

Conventional therapy of brain tumors
  • Surgery

    Treatment is not available due to serious adverse events

  • X-ray therapy

    Normal tissue damage due t excessive radiation energy

  • Proton therapy and heavy ion therapy

    Only visualized local areas can be treated with proton and heavy ion therapy, so it is not possible to treat invasive tumor that is not visible on CT

Boron Neutron Capture Therapy (BNCT)

▶ Tumor cells invading normal cells

Cell based thearpydestroy infiltrative cancer cells, even invisible tumor cells

04Improving the quality of life of patients with one or two treatments

BNCT can improve the patient’s quality of life with only 1 or 2 treatments without surgery, so it can be a new cancer treatment modality.

  • Chemotherapy

    Many cancers are resistant to conventional therapies Continued treatment required Side effect and financial burden

  • Radiation therapy

    At least 30~40 times treatment
    (5 times/week, difficult to treat in a case of recurrence)

  • Proton therapy

    At least 15~30 procedures required
    (once or twice a week)

  • BNCT

    Once or twice treatment
    (30 minutes to 1 hour per treatment)